Modalert is a widely known brand of modafinil, a eugeroic (wakefulness-promoting agent) primarily used to treat conditions like narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Manufactured by Sun Pharma, Modalert is also popularly used off-label for cognitive enhancement. To understand its effects and safety profile, it’s crucial to examine what exactly goes into each tablet. Here are ingredients of Modalert:
1. Active Ingredient of Modalert: Modafinil
The cornerstone of Modalert is modafinil, a central nervous system stimulant. Here’s an overview of the active component:
- Chemical Name: 2-[(diphenylmethyl)sulfinyl]acetamide
- Concentration per tablet: Typically 100 mg or 200 mg
- Function: Enhances alertness by altering neurotransmitters such as dopamine, norepinephrine, and histamine in the brain.
Mechanism of Action:
Modafinil works by inhibiting the dopamine reuptake transporter (DAT), leading to increased extracellular dopamine levels. Unlike traditional stimulants, it has a lower risk of addiction and fewer cardiovascular side effects.
2. Inactive Ingredients of Modalert (Excipients)
These ingredients play a critical role in the stability, absorption, and appearance of the tablet but do not contribute directly to its pharmacological effects.
a. Lactose Monohydrate
- Purpose: Used as a filler or diluent.
- Consideration: May cause issues in lactose-intolerant individuals.
b. Microcrystalline Cellulose
- Purpose: Acts as a binder and stabilizer.
- Function: Ensures consistent tablet structure and aids in uniform drug dispersion.
c. Povidone (Polyvinylpyrrolidone)
- Purpose: Serves as a binder.
- Function: Enhances the solubility and bioavailability of modafinil.
d. Magnesium Stearate
- Purpose: Functions as a lubricant.
- Function: Prevents tablet ingredients from sticking to manufacturing equipment.
e. Croscarmellose Sodium
- Purpose: Disintegrant.
- Function: Helps the tablet break down quickly once ingested for faster absorption.
f. Talc
- Purpose: Anti-caking agent and glidant.
- Function: Assists in smooth tablet manufacturing and improves shelf-life.
g. Silicon Dioxide
- Purpose: Anti-clumping agent.
- Function: Maintains tablet consistency and prevents degradation.
3. Optional Coating Agents
Some formulations of Modalert may include film coatings for easier swallowing or protection against light and humidity. These may include:
- Hypromellose (HPMC): A cellulose derivative used in coatings.
- Polyethylene Glycol (PEG): A plasticizer in the coating that ensures smooth texture.
- Titanium Dioxide: Often used to give tablets a white or opaque appearance.
4. Ingredients of Modalert: Safety and Allergen Information
While Modalert is generally well tolerated, some of the excipients (especially lactose) may not be suitable for people with specific allergies or intolerances. Always consult a healthcare provider before use, especially if you have:
- Lactose intolerance
- Known allergies to any of the inactive ingredients
- Kidney or liver impairment (as it affects drug metabolism)
Conclusion
Modalert’s effectiveness as a wakefulness-promoting agent largely hinges on its active ingredient, modafinil. However, its formulation is carefully engineered with a suite of inactive ingredients that ensure stability, efficacy, and patient compliance. Many people buy modalert online and this is one of the famous modafinil tradenames. Understanding these components not only informs safe usage but also clarifies potential reactions or side effects, particularly for sensitive individuals.
Always use Modalert under professional guidance, especially when considering off-label cognitive enhancement, and be mindful of the complete ingredient profile before consumption.
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